Article
Heterogeneity of small duct- and large duct-type intrahepatic cholangiocarcinoma.
Histopathology - 1 May 2024
Kinzler Maximilian N, Schulze Falko, Jeroch Jan, Schmitt Christina, Ebner Silvana, Gretser Steffen, Bein Julia, Finkelmeier Fabian, Trojan Jörg, Zeuzem Stefan, Schnitzbauer Andreas A, Demes Melanie C, Reis Henning, Wild Peter J, Walter Dirk
Abstract excerpt
AIMS: The histological subtype of intrahepatic cholangiocarcinoma (iCCA) is associated with different mutational characteristics that impact clinical management. So far, data are lacking on the presence of small duct iCCA (SD-iCCA) and large duct iCCA (LD-iCCA) in a single patient. The aim of the current study was to determine the presence and degree of intratumoural heterogeneity of SD- and LD-iCCA features in...
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