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Article

Single-cell colocalization analysis using a deep generative model.

Cell systems - 21 Feb 2024

Kojima Yasuhiro, Mii Shinji, Hayashi Shuto, Hirose Haruka, Ishikawa Masato, Akiyama Masashi, Enomoto Atsushi, Shimamura Teppei

Abstract excerpt

Analyzing colocalization of single cells with heterogeneous molecular phenotypes is essential for understanding cell-cell interactions, and cellular responses to external stimuli and their biological functions in diseases and tissues. However, existing computational methodologies identified the colocalization patterns between predefined cell populations, which can obscure the molecular signatures arising from...

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PMID: 38387441
DOI: 10.1016/j.cels.2024.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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