A predictive classifier of poor prognosis in transplanted patients with juvenile myelomonocytic leukemia: a study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire.

doi:10.3324/haematol.2023.284103

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Article

A predictive classifier of poor prognosis in transplanted patients with juvenile myelomonocytic leukemia: a study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire.

Haematologica - 1 Sept 2024

Meyran Déborah, Arfeuille Chloé, Chevret Sylvie, Neven Quentin, Caye-Eude Aurélie, Lainey Elodie, Petit Arnaud, Rialland Fanny, Michel Gérard, Plantaz Dominique, Jubert Charlotte, Theron Alexandre, Gandemer Virginie, Ouachée-Chardin Marie, Paillard Catherine, Bruno Bénédicte, Buchbinder Nimrod, Pochon Cécile, Calvo Charlotte, Fahd Mony, Baruchel André, Cavé Hélène, Dalle Jean-Hugues, Strullu Marion

Abstract excerpt

Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric myeloproliferative neoplasm requiring hematopoietic stem cell transplantation (HSCT) in most cases. We retrospectively analyzed 119 JMML patients who underwent first allogeneic HSCT between 2002 and 2021. The majority (97%) carried a RAS-pathway mutation, and 62% exhibited karyotypic alterations or additional mutations in SETBP1, ASXL1, JAK3...

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Identifiers

PMID: 38385260
DOI: 10.3324/haematol.2023.284103
PMCID: PMC11367243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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