Nanopore adaptive sampling effectively enriches bacterial plasmids

Abstract excerpt

ABSTRACT Bacterial plasmids play a major role in the spread of antibiotic resistance genes. However, their characterization via DNA sequencing suffers from the low abundance of plasmid DNA in those samples. Although sample preparation methods can enrich the proportion of plasmid DNA before sequencing, these methods are expensive and laborious, and they might introduce a bias by enriching only for specific plasmid...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genomics and Phylogenetic Studies
• Share to Infections and bacterial resistance
• Share to Infective Endocarditis Diagnosis and Management