Article
RBFOX1, encoding a splicing regulator, is a candidate gene for aggressive behavior.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2020
Fernàndez-Castillo Noèlia, Gan Gabriela, van Donkelaar Marjolein M J, Vaht Mariliis, Weber Heike, Retz Wolfgang, Meyer-Lindenberg Andreas, Franke Barbara, Harro Jaanus, Reif Andreas, Faraone Stephen V, Cormand Bru
Abstract excerpt
The RBFOX1 gene (or A2BP1) encodes a splicing factor important for neuronal development that has been related to autism spectrum disorder and other neurodevelopmental phenotypes. Evidence from complementary sources suggests that this gene contributes to aggressive behavior. Suggestive associations with RBFOX1 have been identified in genome-wide association studies (GWAS) of anger, conduct disorder, and aggressive...
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