Article
Genetic variation in the BLM gene and its expression in the ovaries is closely related to kidding number in goats.
Theriogenology - 1 Apr 2024
An Dongwei, Chen Xiang, Li Ziyang, Dai Lingang, Huang Jiajin, Xiao Meimei, Liu Huan, Xu Jiali, Ruan Yong
Abstract excerpt
Bloom (BLM) helicase plays an important role in DNA replication and the maintenance of genome integrity. BLM protein deficiency, which plays a vital role in the sperm-egg union and germ-cell development during reproduction, can lead to severe DNA damage in goats. However, the effect of BLM protein deficiency on goat litter size has not been reported. Herein, we studied the association between the genetic...
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