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Whole-genome resequencing reveals new mutations in candidate genes for Beichuan-white goat prolificacya.

Animal biotechnology - 1 Nov 2024

Zhou Aimin, Ding Yi, Zhang Xiaohui, Zhou Yugang, Liu Yadong, Li Tingjian, Xiao Long

Abstract excerpt

In this study, we evaluated the copy number variation in the genomes of two groups of Beichuan-white goat populations with large differences in litter size by FST method, and identified 1739 genes and 485 missense mutations in the genes subject to positive selection. Through functional enrichment, ITGAV, LRP4, CDH23, TPRN, RYR2 and CELSR1 genes, involved in embryonic morphogenesis, were essential for litter size...

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PMID: 37729465
DOI: 10.1080/10495398.2023.2258166

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