Article
Novel 12-bp deletion in the coding region of the bovine NPM1 gene affects growth traits.
Journal of applied genetics - 1 Jan 2010
Huang Y-Z, Zhang E-P, Chen H, Wang J, Li Z-J, Huai Y-T, Ma L, Lan X-Y, Ren G, Lei C-Z, Fang X-T, Wang J-Q
Abstract excerpt
The nucleophosmin 1 gene (NPM1) encodes a multifunctional nucleolar phosphoprotein that plays a crucial role in the control of various aspects of cell growth and homeostasis. In this study, the coding region of the NPM1 gene was screened in 1035 individuals of 4 Chinese cattle breeds by DNA sequencing and polyacrylamide gel electrophoresis. A novel 12-bp deletion mutation was identified in the coding region of...
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