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Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells

24 Mar 2011

Abstract excerpt

Differentiation of human induced pluripotent stem cells (hiPSCs) and embryonic stem cells (hESCs) into the erythroid lineage of cells offers a novel opportunity to study erythroid development, regulation of globin switching, drug testing, and modeling of red blood cell (RBC) diseases in vitro. Here we describe an approach for the efficient generation of RBCs from hiPSC/hESCs using an OP9 coculture system to...

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PMID: 21434814
DOI: 10.1089/scd.2011.0078

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