Diversity of major histocompatibility complex (MHC) and natural killer cell receptor (NKR) genes and their interactions in domestic horses.

doi:10.1111/tan.15387

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Article

Diversity of major histocompatibility complex (MHC) and natural killer cell receptor (NKR) genes and their interactions in domestic horses.

HLA - 1 Feb 2024

Bubenikova Jana, Plasil Martin, Futas Jan, Stejskalova Karla, Klumplerova Marie, Oppelt Jan, Suchentrunk Franz, Burger Pamela A, Horin Petr

Abstract excerpt

The immunogenome is the part of the genome that underlies immune mechanisms and evolves under various selective pressures. Two complex regions of the immunogenome, major histocompatibility complex (MHC) and natural killer cell receptor (NKR) genes, play an important role in the response to selective pressures of pathogens. Their importance is expressed by their genetic polymorphism at the molecular level, and...

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PMID: 38358031
DOI: 10.1111/tan.15387

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