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Article

Torch-eCpG: a fast and scalable eQTM mapper for thousands of molecular phenotypes with graphical processing units.

BMC bioinformatics - 14 Feb 2024

Kober Kord M, Berger Liam, Roy Ritu, Olshen Adam

Abstract excerpt

BACKGROUND: Gene expression may be regulated by the DNA methylation of regulatory elements in cis, distal, and trans regions. One method to evaluate the relationship between DNA methylation and gene expression is the mapping of expression quantitative trait methylation (eQTM) loci (also called expression associated CpG loci, eCpG). However, no open-source tools are available to provide eQTM mapping. In addition,...

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PMID: 38355413
DOI: 10.1186/s12859-024-05670-4
PMCID: PMC10867984

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