Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signaling

10 Feb 2024

Abstract excerpt

Previous study showed that higher expression of prolactin (PRL) was found in CRPC samples compared with hormone-naive prostate cancer (HNPC) and benign prostatic hyperplasia (BPH) samples. We further investigate the function of PRL in prostate cancer (PCa) and explored its downstream effects. We found heterogeneous expression of the PRLR in clinical prostate samples. The VCaP and 22Rv1 cells exhibited PRLR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Receptor Mechanisms and Signaling
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38341429
DOI: 10.1038/s41419-023-06362-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signalingPMID 38341429Read ↗

Transcription Factor Stat5 Synergizes with Androgen Receptor in Prostate Cancer CellsSemantic proximity Read ↗

Transcription Factors in Prostate Cancer: Insights for Disease Development and Diagnostic and Therapeutic ApproachesSemantic proximity Read ↗

Androgen signaling and its interactions with other signaling pathways in prostate cancerSemantic proximity Read ↗

Identification of Potential Key Genes in Prostate Cancer with Gene Expression, Pivotal Pathways and Regulatory Networks Analysis Using Integrated Bioinformatics MethodsSemantic proximity Read ↗

Impact of STAT Proteins in Tumor Progress and Therapy Resistance in Advanced and Metastasized Prostate CancerSemantic proximity Read ↗

Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challengesSemantic proximity Read ↗

Structure and Function of the Nuclear Receptor Superfamily and Current Targeted Therapies of Prostate CancerSemantic proximity Read ↗

Reciprocal regulation between RACGAP1 and AR contributes to endocrine therapy resistance in prostate cancerSemantic proximity Read ↗

Androgen receptor signaling in prostate cancer development and progressionSemantic proximity Read ↗

AR Signaling and the PI3K Pathway in Prostate CancerSemantic proximity Read ↗

The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate CancerSemantic proximity Read ↗

Expression and ERG regulation of PIM kinases in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.