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Article

Causal relationships of Janus kinase 2 with chronic kidney diseases: a two-sample Mendelian randomisation study.

Clinical and experimental nephrology - 1 Feb 2026

Wang Yanjun, Ding Yanling, Zhang Jiatong, Wuren Tana

Abstract excerpt

BACKGROUND: The role of Janus kinase (JAK) 2 in chronic kidney disease (CKD) remains unreported. This Mendelian randomisation (MR) study investigates the causal associations of JAK2 with CKD and provides references for the identification of possible therapeutic targets and the prevention of renal dysfunction. METHODS: Summary data for JAK2 and various CKD endpoints are extracted from genome-wide association study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41284113
DOI: 10.1007/s10157-025-02791-9

Genes

JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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