Article
Immune responses to P falciparum antibodies in symptomatic malaria patients with variant hemoglobin genotypes in Ghana.
BMC immunology - 9 Feb 2024
Asare Kwame Kumi, Agrah Benjamin, Ofori-Acquah Fiifi Solomon, Kudzi William, Aryee Nii Ayite, Amoah Linda Eva
Abstract excerpt
BACKGROUND: Haemoglobin (Hb) variants such as sickle cell trait (SCT/HbAS) play a role in protecting against clinical malaria, but little is known about the development of immune responses against malaria parasite (Plasmodium falciparum surface protein 230 (Pfs230) and Plasmodium falciparum erythrocyte binding antigen 175 region-3 (PfEBA175-3R)) and vector (on the An. gambiae Salivary Gland Protein-6 peptide 1...
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