Article
Genetic Analysis of Obstructive Sleep Apnea and Its Relationship with Severe COVID-19.
Annals of the American Thoracic Society - 1 Jun 2024
Strausz Satu, Agafonova Elizabete, Tiullinen Varvara, Kiiskinen Tuomo, Broberg Martin, Ruotsalainen Sanni E, Koskela Jukka, Bachour Adel, Sofer Tamar, Gottlieb Daniel J, Palotie Aarno, Palotie Tuula, Ripatti Samuli, Ollila Hanna M
Abstract excerpt
Rationale: Although patients with obstructive sleep apnea (OSA) have a higher risk for coronavirus disease (COVID-19) hospitalization, the causal relationship has remained unexplored. Objectives: To understand the causal relationship between OSA and COVID-19 by leveraging data from vaccination and electronic health records, genetic risk factors from genome-wide association studies, and Mendelian randomization....
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