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Article

Type 2M/2A von Willebrand disease: a shared phenotype between type 2M and 2A.

Blood advances - 9 Apr 2024

Seidizadeh Omid, Mollica Luca, Zambarbieri Serena, Baronciani Luciano, Cairo Andrea, Colpani Paola, Cozzi Giovanna, Pagliari Maria Teresa, Ciavarella Alessandro, Siboni Simona M, Peyvandi Flora

Abstract excerpt

ABSTRACT: Four variants have been continuously subjected to debate and received different von Willebrand disease (VWD) classifications: p.R1315L, p.R1315C, p.R1374H, and p.R1374C. We chose to comprehensively investigate these variants with full set of VWD tests, protein-modeling predictions and applying structural biology. Patients with p.R1315L, p.R1315C, p.R1374H, and p.R1374C were included. A group with type...

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Identifiers

PMID: 38315875
DOI: 10.1182/bloodadvances.2024012626
PMCID: PMC10997909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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