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Article

Landscape and Spectrum of VWF Variants in Type 2 Von Willebrand Disease: Insights from a German Patient Cohort.

Thrombosis and haemostasis - 1 Feb 2026

Yadegari Hamideh, Halimeh Susan, Krahforst Alexander, Pavlova Anna, Pezeshkpoor Behnaz, Müller Jens, Pötzsch Bernd, Biswas Arijit, Marquardt Natascha, Scholz Ute, Richter Heinrich, Trobisch Heiner, Liebscher Karin, Olivieri Martin, Trautmann-Grill Karolin, Tiebel Oliver, Knöfler Ralf, Oldenburg Johannes

Abstract excerpt

von Willebrand disease (VWD) type 2 arises from variants in von Willebrand factor (VWF) that disrupt its essential hemostatic functions. As per ISTH guidelines, it is classified as type 2A, 2B, 2M, and 2N based on the affected VWF roles.This population-based study aims to uncover the genotype and laboratory phenotypes in type 2 VWD, providing insights into underlying genetics and genotype-phenotype...

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Identifiers

PMID: 40393667
DOI: 10.1055/a-2616-5161
PMCID: PMC12858306

Genes

VWF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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