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Identification of STAT3 as a biomarker for cellular senescence in liver fibrosis: A bioinformatics and experimental validation study

28 Jan 2024

Abstract excerpt

BACKGROUND: Cellular senescence is associated with a dysregulated inflammatory response, which is an important driver of the development of liver fibrosis (LF). This study aimed to investigate the effect of cellular senescence on LF and identify potential key biomarkers through bioinformatics analysis combined with validation experiments in vivo and in vitro. METHODS: The Gene Expression Omnibus (GEO) database...

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Share to Liver Disease Diagnosis and Treatment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38286349
DOI: 10.1016/j.ygeno.2024.110800

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