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Article

CERS6-AS1 contributes to the malignant phenotypes of colorectal cancer cells by interacting with miR-15b-5p to regulate SPTBN2.

The Kaohsiung journal of medical sciences - 1 May 2022

Zhao Shi-Yu, Wang Zhi, Wu Xiang-Bai, Zhang Shuai, Chen Qiao, Wang Dong-Dong, Tan Qiong-Feng

Abstract excerpt

Accumulating evidence indicates that long noncoding RNAs (lncRNAs) act as tumor promoters or suppressors in various types of cancer. Previous investigations suggest that ceramide synthase 6 (CERS6) antisense RNA 1 (CERS6-AS1) acts as an oncogene in breast cancer; however, its role in colorectal cancer is unknown. This study aimed to explore the molecular mechanism of CERS6-AS1 in colorectal cancer. Gene...

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Identifiers

PMID: 35146902
DOI: 10.1002/kjm2.12503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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