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Article

The Interaction between CLSPN Gene Polymorphisms and Alcohol Consumption Contributes to Oral Cancer Progression.

International journal of molecular sciences - 16 Jan 2024

Hsieh Ming-Ju, Lo Yu-Sheng, Ho Hsin-Yu, Lin Chia-Chieh, Chuang Yi-Ching, Chen Mu-Kuan

Abstract excerpt

Most disease single nucleotide polymorphisms (SNPs) are regulatory and approximately half of heritability is occupied by the top 1% of genes, with the gene-level structure varying with the number of variants associated with the most common alleles. Cancer occurrence and progression are significantly affected by Claspin (CLSPN) gene polymorphism present in the population, which alters the expression, function, and...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Squamous Cell Carcinoma of Head and Neck

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Identifiers

PMID: 38256171
DOI: 10.3390/ijms25021098
PMCID: PMC10816373

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