Identification of diagnostic molecules and potential traditional Chinese medicine components for Alzheimer’s disease by single cell RNA sequencing combined with a systematic framework for network pharmacology

Abstract excerpt

Background Single-cell RNA sequencing (scRNA-Seq) provides new perspectives and ideas to investigate the interactions between different cell types and organisms. By integrating scRNA-seq with new computational frameworks or specific technologies, better Alzheimer’s disease (AD) treatments may be developed. Methods The single-cell sequencing dataset GSE158234 was obtained from the GEO database. Preprocessing,...

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