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The Emerging Roles for Telomerase in the Central Nervous System

16 May 2018

Abstract excerpt

Telomerase, a specialized ribonucleoprotein enzyme complex, maintains telomere length at the 3' end of chromosomes, and functions importantly in stem cells, cancer and aging. Telomerase exists in neural stem cells (NSCs) and neural progenitor cells (NPCs), at a high level in the developing and adult brains of humans and rodents. Increasing studies have demonstrated that telomerase in NSCs/NPCs plays important...

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PMID: 29867352
DOI: 10.3389/fnmol.2018.00160

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