Article
Harnessing function of EMT in cancer drug resistance: a metastasis regulator determines chemotherapy response.
Cancer metastasis reviews - 1 Mar 2024
Ebrahimi Nasim, Manavi Mahdokht Sadat, Faghihkhorasani Ferdos, Fakhr Siavash Seifollahy, Baei Fatemeh Jafari, Khorasani Fereshteh Faghih, Zare Mohammad Mehdi, Far Nazanin Pazhouhesh, Rezaei-Tazangi Fatemeh, Ren Jun, Reiter Russel J, Nabavi Noushin, Aref Amir Reza, Chen Chu, Ertas Yavuz Nuri, Lu Qi
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is a complicated molecular process that governs cellular shape and function changes throughout tissue development and embryogenesis. In addition, EMT contributes to the development and spread of tumors. Expanding and degrading the surrounding microenvironment, cells undergoing EMT move away from the main location. On the basis of the expression of fibroblast-specific...
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