Article
Genome-Wide Interaction Analysis With DASH Diet Score Identified Novel Loci for Systolic Blood Pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2024
Guirette Mélanie, Lan Jessie, McKeown Nicola M, Brown Michael R, Chen Han, de Vries Paul S, Kim Hyunju, Rebholz Casey M, Morrison Alanna C, Bartz Traci M, Fretts Amanda M, Guo Xiuqing, Lemaitre Rozenn N, Liu Ching-Ti, Noordam Raymond, de Mutsert Renée, Rosendaal Frits R, Wang Carol A, Beilin Lawrence J, Mori Trevor A, Oddy Wendy H, Pennell Craig E, Chai Jin Fang, Whitton Clare, van Dam Rob M, Liu Jianjun, Tai E Shyong, Sim Xueling, Neuhouser Marian L, Kooperberg Charles, Tinker Lesley F, Franceschini Nora, Huan TianXiao, Winkler Thomas W, Bentley Amy R, Gauderman W James, Heerkens Luc, Tanaka Toshiko, van Rooij Jeroen, Munroe Patricia B, Warren Helen R, Voortman Trudy, Chen Honglei, Rao D C, Levy Daniel, Ma Jiantao
Abstract excerpt
BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet score lowers blood pressure (BP). We examined interactions between genotype and the DASH diet score in relation to systolic BP. METHODS: We analyzed up to 9 420 585 single nucleotide polymorphisms in up to 127 282 individuals of 6 population groups (91% of European population) from the Cohorts for Heart and Aging Research in Genomic Epidemiology...
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