Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study.

doi:10.1038/s41380-023-02383-7

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Article

Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study.

Molecular psychiatry - 1 Apr 2024

Frach Leonard, Barkhuizen Wikus, Allegrini Andrea G, Ask Helga, Hannigan Laurie J, Corfield Elizabeth C, Andreassen Ole A, Dudbridge Frank, Ystrom Eivind, Havdahl Alexandra, Pingault Jean-Baptiste

Abstract excerpt

The aetiology of conduct problems involves a combination of genetic and environmental factors, many of which are inherently linked to parental characteristics given parents' central role in children's lives across development. It is important to disentangle to what extent links between parental heritable characteristics and children's behaviour are due to transmission of genetic risk or due to parental indirect...

Topics

Humans
Female
Child
Norway
Male
Adolescent
Risk Factors
Multifactorial Inheritance
Cohort Studies
Conduct Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adult

Mothers

Fathers

Problem Behavior

Genetic Predisposition to Disease

Genotype

Source

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Identifiers

PMID: 38225381
DOI: 10.1038/s41380-023-02383-7
PMCID: PMC11176059

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