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Article

Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection.

Virus research - 1 Mar 2024

Powers John M, Leist Sarah R, Mallory Michael L, Yount Boyd L, Gully Kendra L, Zweigart Mark R, Bailey Alexis B, Sheahan Timothy P, Harkema Jack R, Baric Ralph S

Abstract excerpt

Following the emergence of B.1.1.529 Omicron, the SARS-CoV-2 virus evolved into a significant number of sublineage variants that possessed numerous mutations throughout the genome, but particularly within the spike glycoprotein (S) gene. For example, the BQ.1.1 and the XBB.1 and XBB.1.5 subvariants contained 34 and 41 mutations in S, respectively. However, these variants elicited largely replication only or mild...

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Identifiers

PMID: 38224840
DOI: 10.1016/j.virusres.2024.199319
PMCID: PMC10835285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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