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Article

Leiomyoma and the importance of genetic variation on genes related to the vasculature system - CβS, MTHFR, NOS3, CYBA, and ACE1.

European journal of obstetrics, gynecology, and reproductive biology - 1 Mar 2024

Inácio Ângela, Aguiar Laura, Rodrigues Beatriz, Pires Patrícia, Ferreira Joana, Bilhim Tiago, Pisco João, Bicho Manuel, Clara Bicho Maria

Abstract excerpt

OBJECTIVE: The link between the systemic vasculature system and tumor biology is here investigated by studying the contribution of CβS (844ins68), MTHFR (677C > T), NOS3 (4a/4b), CYBA (C242T), and ACE1 (I/D) genes to leiomyoma onset, uterus and leiomyoma volumes. METHODS: DNA samples from 130 women with leiomyomas and 527 from healthy women were genotyped by PCR or PCR-RFLP. Qui-square (χ2) or Fisher's exact test...

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PMID: 38218160
DOI: 10.1016/j.ejogrb.2024.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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