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Article

Recurrent Aortic Thromboembolism Associated With TET2 Mutation in Chronic Myelomonocytic Leukemia.

Journal of investigative medicine high impact case reports - 1 Jan 2000

Bukhari Syed, Saati Ammar, Abuhalimeh Batool, Ouma Geoffrey

Abstract excerpt

Ten-eleven translocation 2 (TET2) plays a pivotal role in epigenetic regulation, cell differentiation, and the inflammatory response. It also mediates the transcriptional regulation for inflammatory cytokines, particularly interleukin-6. While loss-of-function mutation in TET2 has been associated with hematological malignancies, it has been increasingly recognized to cause atherosclerotic disease. The increased...

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Identifiers

PMID: 38214069
DOI: 10.1177/23247096231224366
PMCID: PMC10787530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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