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Article

Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation.

Annals of hematology - 1 Feb 2010

De Stefano Valerio, Za Tommaso, Rossi Elena, Vannucchi Alessandro M, Ruggeri Marco, Elli Elena, Micò Caterina, Tieghi Alessia, Cacciola Rossella R, Santoro Cristina, Vianelli Nicola, Guglielmelli Paola, Pieri Lisa, Scognamiglio Francesca, Cacciola Emma, Rodeghiero Francesco, Pogliani Enrico M, Finazzi Guido, Gugliotta Luigi, Leone Giuseppe, Barbui Tiziano

Abstract excerpt

Evidence suggests that the JAK2 V617F mutation is associated with an increased risk of first thrombosis in patients with essential thrombocythemia (ET). Whether this mutation is also a risk factor for recurrent thrombosis is currently unknown. To investigate the impact of the JAK2 V617F mutation...

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Source

Identifiers

PMID: 19582452
DOI: 10.1007/s00277-009-0788-5

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19582452-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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