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Article

Balance of activity during a critical period tunes a developing network.

eLife - 9 Jan 2024

Hunter Iain, Coulson Bramwell, Pettini Tom, Davies Jacob J, Parkin Jill, Landgraf Matthias, Baines Richard A

Abstract excerpt

Developing neural circuits are influenced by activity and are especially sensitive to changes in activity during critical periods (CPs) of development. Changes occurring during a CP often become 'locked in' so that they affect the mature network. Indeed, several neurodevelopmental disorders have been linked to excessive activity during such periods. It is, therefore, important to identify those aspects of neural...

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Identifiers

PMID: 38193543
DOI: 10.7554/eLife.91599
PMCID: PMC10945558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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