Article
Blood group genotyping: the power and limitations of the Hemo ID Panel and MassARRAY platform.
Immunohematology - 1 Jan 2015
McBean Rhiannon S, Hyland Catherine A, Flower Robert L
Abstract excerpt
Matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry (MALDI-TOF MS), is a sensitive analytical method capable of resolving DNA fragments varying in mass by a single nucleotide. MALDI-TOF MS is applicable to blood group genotyping, as the majority of blood group antigens are encoded by single nucleotide polymorphisms. Blood group genotyping by MALDI-TOF MS can be performed using a panel...
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