Article
The Research of a Large-Scale Analysis Platform for MNS Blood Group Identification Based on Long-Read Sequencing.
Transfusion medicine reviews - 1 Oct 2024
Xu Hua, Su Xiaomin, Zuo Qinqin, Zhang Liangzi, Chu Xiaoyue
Abstract excerpt
The objective of this study was to devise a novel approach for determining MNS blood group utilizing long-read sequencing (LRS) and to identify intricate genome variations associated with this blood group system. In this study, a total of 60 blood samples were collected from randomly selected Chinese Han blood donors. The amplification of the full-length sequences of GYPA exon 2-7 (11 kb) and GYPB exon 2-6 (7 kb)...
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