Refining mutanome-based individualised immunotherapy of melanoma using artificial intelligence.

doi:10.1186/s40001-023-01625-2

Article

Refining mutanome-based individualised immunotherapy of melanoma using artificial intelligence.

European journal of medical research - 5 Jan 2024

Zakariya Farida, Salem Fatma K, Alamrain Abdulwhhab Abu, Sanker Vivek, Abdelazeem Zainab G, Hosameldin Mohamed, Tan Joecelyn Kirani, Howard Rachel, Huang Helen, Awuah Wireko Andrew

Abstract excerpt

Using the particular nature of melanoma mutanomes to develop medicines that activate the immune system against specific mutations is a game changer in immunotherapy individualisation. It offers a viable solution to the recent rise in resistance to accessible immunotherapy alternatives, with some patients demonstrating innate resistance to these drugs despite past sensitisation to these agents. However, various...

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