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Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma

29 Dec 2023

Abstract excerpt

BACKGROUND: It is of great clinical significance to find out the ideal tumor biomarkers and therapeutic targets to improve the prognosis of patients with osteosarcoma (OS). Oxidative stress (OXS) can directly target intracellular macromolecules and exhibit dual effects of tumor promotion and suppression. METHODS: OXS-related genes (OXRGs) were extracted from public databases, including TARGET and GEO. Univariate...

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PMID: 38180104
DOI: 10.18632/aging.205354

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