Article
Impact of elexacaftor/tezacaftor/ivacaftor on lipid and fat-soluble vitamin levels and association with body mass index.
Pediatric pulmonology - 1 Mar 2024
Patel Tanvi, McBennett Kimberly, Sankararaman Senthilkumar, Schindler Teresa, Sundaram Krithika, Minich Nori Mercuri, Malay Sindhoosha, Kutney Katherine
Abstract excerpt
INTRODUCTION: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve gastrointestinal absorption of nutrients and may result in changes in body mass index (BMI), serum lipids, and fat-soluble vitamin levels. We hypothesized that serum lipids and vitamin levels would increase with CFTR modulator therapy and that greater increase in lipids and vitamin levels would be related to greater...
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