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Article

Impact of elexacaftor/tezacaftor/ivacaftor on vitamin D absorption in cystic fibrosis patients.

Pediatric pulmonology - 1 Mar 2022

Wright Brittany A, Ketchen Natalie K, Rasmussen Leah N, Bartels Alyssa R, Singh Sachinkumar B

Abstract excerpt

BACKGROUND: Cystic fibrosis (CF) is a multisystem disorder that results in the buildup of mucus in various organs. Ninety percent of CF patients are classified as pancreatic insufficient, leading to malabsorption of nutrients and fat-soluble vitamins without the assistance of exogenous pancreatic enzymes. This study was designed to determine if serum 25-hydroxyvitamin D concentrations were impacted by initiation...

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PMID: 34859619
DOI: 10.1002/ppul.25781

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