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Article

Proteomic Biomarkers of Intrahepatic Cholestasis of Pregnancy

4 Jan 2024

Abstract excerpt

Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disease, which can lead to adverse fetal outcomes, including preterm labor and intrauterine death. The pathogenesis of ICP is still unclear. We hypothesized that pathological index leads to abnormal placenta changes in ICP. Investigation of these differences in protein expression in parallel profiling is essential to understand the...

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PMID: 38177949
DOI: 10.1007/s43032-023-01437-z

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