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A Lipopolysaccharide-Enriched Cow’s Milk Allergy Microbiome Promotes a TLR4-Dependent Proinflammatory Intestinal Immune Response

3 Jan 2024

Abstract excerpt

We have previously reported that the gut microbiota of healthy infants harbors allergy-protective bacteria taxa that are depleted in infants with cow's milk allergy (CMA). Few reports have investigated the role of the gut microbiota in promoting allergic responses. In this study we selected a CMA-associated microbiota with increased abundance of Gram-negative bacteria for analysis of its proinflammatory...

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PMID: 38169331
DOI: 10.4049/jimmunol.2300518

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