Article
Genomic Analysis of Rwandan G9P[8] Rotavirus Strains Pre- and Post-RotaTeq® Vaccine Reveals Significant Distinct Sub-Clustering in a Post-Vaccination Cohort.
Viruses - 25 Nov 2023
Potgieter Robyn-Lee, Mwangi Peter N, Mogotsi Milton T, Uwimana Jeannine, Mutesa Leon, Muganga Narcisse, Murenzi Didier, Tusiyenge Lisine, Seheri Mapaseka L, Steele A Duncan, Mwenda Jason M, Nyaga Martin M
Abstract excerpt
Although the introduction of rotavirus vaccines has substantially contributed to the reduction in rotavirus morbidity and mortality, concerns persist about the re-emergence of variant strains that might alter vaccine effectiveness in the long term. The G9 strains re-emerged in Africa during the mid-1990s and have more recently become predominant in some countries, such as Ghana and Zambia. In Rwanda, during the...
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