Article
Whole genome and in-silico analyses of G1P[8] rotavirus strains from pre- and post-vaccination periods in Rwanda.
Scientific reports - 10 Aug 2020
Rasebotsa Sebotsana, Mwangi Peter N, Mogotsi Milton T, Sabiu Saheed, Magagula Nonkululeko B, Rakau Kebareng, Uwimana Jeannine, Mutesa Leon, Muganga Narcisse, Murenzi Didier, Tuyisenge Lisine, Jaimes Jose, Esona Mathew D, Bowen Michael D, Mphahlele M Jeffrey, Seheri Mapaseka L, Mwenda Jason M, Nyaga Martin M
Abstract excerpt
Rwanda was the first low-income African country to introduce RotaTeq vaccine into its Expanded Programme on Immunization in May 2012. To gain insights into the overall genetic make-up and evolution of Rwandan G1P[8] strains pre- and post-vaccine introduction, rotavirus positive fecal samples collected between 2011 and 2016 from children under the age of 5 years as part of ongoing surveillance were genotyped with...
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