Article
Evolutionary changes between pre- and post-vaccine South African group A G2P[4] rotavirus strains, 2003-2017.
Microbial genomics - 1 Apr 2022
Mwangi Peter N, Page Nicola A, Seheri Mapaseka L, Mphahlele M Jeffrey, Nadan Sandrama, Esona Mathew D, Kumwenda Benjamin, Kamng'ona Arox W, Donato Celeste M, Steele Duncan A, Ndze Valantine N, Dennis Francis E, Jere Khuzwayo C, Nyaga Martin M
Abstract excerpt
The transient upsurge of G2P[4] group A rotavirus (RVA) after Rotarix vaccine introduction in several countries has been a matter of concern. To gain insight into the diversity and evolution of G2P[4] strains in South Africa pre- and post-RVA vaccination introduction, whole-genome sequencing was performed for RVA positive faecal specimens collected between 2003 and 2017 and samples previously sequenced were...
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