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Urinary Innate-Immunity Biomarkers and Serum Vitamin D in Children with CAKUT: sTLR4 as a Potential Predictor of Future Urinary Tract Infection

2026-06-16

Abstract excerpt

<title>Abstract</title> <p>Background Children with congenital anomalies of the kidney and urinary tract (CAKUT) are predisposed to develop urinary tract infections (UTIs). Urinary heat-shock protein 70 (HSP70) and soluble Toll-like receptor 4 (sTLR4) have emerged as markers of urinary tract inflammation, while serum 25-hydroxyvitamin D [25(OH)D] has been implicated in mucosal host defense. However, their combin...

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Literature Corpus work
30fd9c7b-bf1d-5c25-b8ba-3b60938f81b4
DOI
10.21203/rs.3.rs-9950005/v1
Open publication

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