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Article

AKR1C1 and hormone metabolism in lipedema pathogenesis: a computational biology approach.

1 Dec 2023

Abstract excerpt

OBJECTIVE: Lipedema is an autosomal dominant genetic disease that mainly affects women. It is characterized by excess deposition of subcutaneous adipose tissue, pain, and anxiety. The genetic and environmental etiology of lipedema is still largely unknown. Although considered a rare disease, this pathology has been suggested to be underdiagnosed or misdiagnosed as obesity or lymphedema. Steroid hormones seem to...

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Identifiers

PMID: 38112954
DOI: 10.26355/eurrev_202312_34698

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