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Article

MKRN3 circulating levels in girls with central precocious puberty caused by MKRN3 gene mutations.

Journal of endocrinological investigation - 1 Jun 2024

Aiello F, Palumbo S, Cirillo G, Tornese G, Fava D, Wasniewska M, Faienza M F, Bozzola M, Luongo C, Festa A, Miraglia Del Giudice E, Grandone A

Abstract excerpt

PURPOSE: MKNR3 is a paternally expressed gene whose mutations are the main cause of central precocious puberty (CPP). Protein circulating levels can be easily measured, as demonstrated in idiopathic CPP and healthy controls. No data are available for patients harboring an MKRN3 mutation. Our aim was to perform MKRN3 mutation screening and to investigate if circulating protein levels could be a screening tool to...

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PMID: 38112911
DOI: 10.1007/s40618-023-02255-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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