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Article

Investigation of MKRN3 Mutation in Patients with Familial Central Precocious Puberty

Journal of clinical research in pediatric endocrinology - 31 Jul 2018

Aycan Zehra, Savaş-Erdeve Şenay, Çetinkaya Semra, Kurnaz Erdal, Keskin Melikşah, Muratoğlu Şahin Nursel, Bayramoğlu Elvan, Ceylaner Gülay

Abstract excerpt

Objective: There have been recent advances in the understanding of the etiology of idiopathic central precocious puberty (iCPP) including new genetic associations. The aim of this clinical study was to determine the frequency of MKRN3 mutation in cases of familial iCPP. Methods: Potential sequence variations in the maternally imprinted MKRN3 gene were evaluated in 19 participants from 10 families using...

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Identifiers

PMID: 29537379
DOI: 10.4274/jcrpe.5506
PMCID: PMC6083467

Genes

MKRN3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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