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Tandem gene duplications contributed to high-level azole resistance in a rapidly expanding Candida tropicalis population

15 Dec 2023

Abstract excerpt

Abstract Invasive diseases caused by the globally distributed commensal yeast Candida tropicalis are associated with mortality rates of greater than 50%. Notable increases of azole resistance have been observed in this species, particularly within Asia-Pacific regions. Here, we carried out a genetic population study on 1571 global C. tropicalis isolates using multilocus sequence typing (MLST). In addition,...

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PMID: 38102133
DOI: 10.1038/s41467-023-43380-2

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