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Article

Stability of circulating miRNA in saliva: The influence of sample associated pre-analytical variables

12 Dec 2023

Abstract excerpt

BACKGROUND AND AIMS: Increasing evidence supports the practicability of salivary cell-free (cf) miRNA as liquid biopsy markers in cancers. Its successful translation in the clinical setting requires reproducible approaches for saliva manipulation, in order to control for pre-analytical variables influencing miRNA stability. This study aims to define the optimal conditions to maintain the integrity of saliva...

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PMID: 38097127
DOI: 10.1016/j.cca.2023.117702

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