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Evaluating Pre-Analytical Variables for Saliva Cell-Free DNA Liquid Biopsy

9 May 2023

Abstract excerpt

Liquid biopsy utilizing cell-free DNA (cfDNA) has become an emergent field of study for cancer screening and monitoring. While blood-based liquid biopsy has been investigated extensively, there are advantages to using other body fluids. Using saliva is noninvasive, repeatable, and it may be enriched with cfDNA from certain cancer types. However, the lack of standardization in the pre-analytical phase of...

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PMID: 37238150
DOI: 10.3390/diagnostics13101665

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