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Isolation of salivary cell-free DNA for cancer detection

2 May 2023

Abstract excerpt

Saliva is an emerging source of disease biomarkers, particularly for cancers of the head and neck. Although analysis of cell-free DNA (cfDNA) in saliva holds promise as a liquid biopsy for cancer detection, currently there are no standardized methodologies for the collection and isolation of saliva for the purposes of studying DNA. Here, we evaluated various saliva collection receptacles and DNA purification...

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PMID: 37130100
DOI: 10.1371/journal.pone.0285214

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