Elevated proton motive force is a tetracycline resistance mechanism that leads to the sensitivity to gentamicin in Edwardsiella tarda

Abstract excerpt

Abstract Tetracycline is a commonly used human and veterinary antibiotic that is mostly discharged into environment and thereby tetracycline‐resistant bacteria are widely isolated. To combat these resistant bacteria, further understanding for tetracycline resistance mechanisms is needed. Here, GC–MS based untargeted metabolomics with biochemistry and molecular biology techniques was used to explore tetracycline...

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